Lamivudine
Product Name: Lamivudine
Synonyms: (-)-BCH-189;(-)-BETA-L-2',3'-DIDEOXY-3'-THIACYTIDINE;(-)-B-L-2',3'-DIDEOXY-3'-THIACYTIDINE;(2r-cis)-4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1h)-pyrimidinone;2'-deoxy-3'-thiacytidine;4-AMINO-1-((2R,5S)-2-HYDROXYMETHYL-[1,3]OXATHIOLAN-5-YL)-1H-PYRIMIDIN-2-ONE;3TC;3'-THIA-2',3'-DIDEOXYCYTIDINE
CAS: 134678-17-4
Assay: 99%
Packing: 25kg/drum
MF: C8H11N3O3S
MW: 229.26
Appearance: White crystal or crystalline powder

Use: lamivudine as antiviral drugs, for the treatment of hepatitis B virus infection in hepatobiliary diseases caused by.

Lamivudine English name for the Lamivudine, chemical name is 2 '3' - dideoxy -3 '- thio cytosine (2' - 3 'deoxy-3' -thiocytidine), also called 3-TC. In Chinese after the listing of the commodity called heptodin. That the randomized controlled clinical trial, a daily dose of 100 mg can significantly inhibit the HBV level of DNA, HBeAg seroconversion rate increased with increasing treatment time, the HbeAg positive patients were treated for 1, 2, 3, 4 and 5 years after HBeAg seroconversion rates were 22%, 29%, 40%, 47% and 50%[1-3] before treatment; higher levels of ALT, HBeAg seroconversion rate was also higher in [56-60]. Long term therapy can reduce inflammation, reduce the incidence of [1,2] in liver fibrosis and cirrhosis. Show that randomized controlled clinical trials, the drug can reduce hepatic decompensation and HCC (hepatocellular carcinoma) incidence of [21]. In patients with decompensated cirrhosis can improve liver function, prolong the survival time of [61- 63]. Foreign studies show, efficacy and adult lamivudine treatment of chronic hepatitis B in children is similar, good safety [64,65].

The hepatitis B patients with lamivudine liver transplantation, transplantation; transplantation, lamivudine combined with HBIG, can significantly reduce the HBV recurrence after liver transplantation, and can reduce the dose of HBIG.
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